South Shields face a trip to Tadcaster Albion in the first round of the Integro Cup.
The Mariners will travel to the BetVictor Northern Premier North West Division side on Tuesday, September 17.
The two sides last met in competitive action in the 2017-18 season, with Shields winning 2-0 at Tadcaster before the reverse fixture was drawn 0-0.
Shields reached the semi-final of the Integro Cup in the same campaign.
Source: SSFC Website